高慧明 教授

发布时间:2020-06-15浏览次数:28

姓名:高慧明


职称:教授

研究方向:神经炎症和氧化应激反应在阿尔茨海默症和帕金森病等神经退行性疾病中的作用和机制,筛选抗炎神经保护药物。

代表性成果:

[1]Zhou, H. et al. CD11b/CD18 (Mac-1) is a novel surface receptor for extracellular double-stranded RNA to mediate cellular inflammatory responses. Journal of immunology 190, 115-125, doi:10.4049/jimmunol.1202136 (2013).

[2]Gao, H. M. et al. HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience 31, 1081-1092, doi:10.1523/JNEUROSCI.3732-10.2011 (2011).

[3]Gao, H. M. et al. Neuroinflammation and oxidation/nitration of alpha-synuclein linked to dopaminergic neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 7687-7698, doi:10.1523/JNEUROSCI.0143-07.2008 (2008).

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